| Business | Phone |
| First Baptist Church Big Pine 300 Key Deer Blvd, Big Pine Key 33043 | (305) 872-2542 |
| Jehovah's Witnesses Us Highway 1, Big Pine Key 33043 | (305) 872-4622 |
| Lord Of The Seas Lutheran Chr 1250 Key Deer Blvd, Big Pine Key 33043 | (305) 872-3612 |
| Methodist Church-Big Pine Untd 280 Key Deer Blvd, Big Pine Key 33043 | (305) 872-2470 |
| St Francis In The Keys 1600 Key Deer Blvd, Big Pine Key 33043 | (305) 872-2547 |
| St Peter Church 31300 Overseas Hwy, Big Pine Key 33043 | (305) 872-2537 |
| Vineyard Christian Church 100 County Rd, Big Pine Key 33043 | (305) 872-3404 |
| Vineyard Christian School County Rd, Big Pine Key 33043 | (305) 872-1252 |
| Jehovah's Witnesses Us Highway 1, Big Pine Key 33043 | (305) 872-4622 |