| Business | Phone |
| Belvedere Motel 3901 Sycamore St, Cairo 62914 | (618) 734-4020 |
| Days Inn Route 57 & Route 3amp;, Cairo 62914 | (618) 734-0215 |
| Relax Inn 214 Washington Ave, Cairo 62914 | (618) 734-0285 |
| Garden Inn Us Highway 51 Route 2, Cairo 62914 | (618) 734-9554 |