| Business | Phone |
| Little Angels Day Care 108 W Jaycee Ave, Effingham 62401 | (217) 342-6848 |
| Little Lamb Early Childhood 1901 S 4th St 4, Effingham 62401 | (217) 342-5454 |
| Little Tykes Daycare 1105 S 4th St, Effingham 62401 | (217) 342-9367 |
| Mother Hubbard's Day Care 1011 E Grove Ave, Effingham 62401 | (217) 342-2273 |
| Raney Street Day Care Inc 1800 S Raney St 1, Effingham 62401 | (217) 347-7474 |
| Son Rise Daycare & Dev Ctr 11009 E Us Highway 40, Effingham 62401 | (217) 347-8995 |
| St John's Eagle's Nest Prschl 901 W Jefferson Ave, Effingham 62401 | (217) 342-6828 |
| Ymca 1208 N Wenthe Dr, Effingham 62401 | (217) 347-5155 |
| Treehouse Day Care & Preschool 2309 Hoffman Dr, Effingham 62401 | (217) 342-7424 |
| Treehouse Too 1207 Network Centre Dr 1, Effingham 62401 | (217) 347-0414 |