| Business | Phone |
| Middlecreek Volunteer Fire 378 Chestnut Grv, Prestonsburg 41653 | (606) 886-9097 |
| Prestonsburg City Fire Dept 200 N Lake Dr, Prestonsburg 41653 | (606) 886-1010 |
| Cow Creek Volunteer Fire Dept 2147 Ky Route 194, Prestonsburg 41653 | (606) 874-9500 |
| Floyd County Emergency & Resce 28 Rescue Ct, Prestonsburg 41653 | (606) 886-8114 |