| Business | Phone |
| Bank Of America 406 S Main St, De Soto 63020 | (636) 337-4411 |
| Southern Commercial Bank 2101 Rock Rd, De Soto 63020 | (636) 586-1411 |
| Eagle Bank & Trust Co 50 Jefferson Sq, De Soto 63020 | (636) 337-3636 |
| First State Community Bank 328 N Main St, De Soto 63020 | (636) 586-8821 |
| National City 2000 Rock Rd, De Soto 63020 | (636) 586-4750 |
| National City Bank 224 S Main St, De Soto 63020 | (636) 586-3338 |