| Business | Phone |
| East Prairie Church Of Christ 309 N Martin St, East Prairie 63845 | (573) 649-3427 |
| First Assembly Of God Church 405 North St, East Prairie 63845 | (573) 649-2067 |
| First Baptist Church 205 Pearl St, East Prairie 63845 | (573) 649-5781 |
| First Christian Church 215 S Washington St, East Prairie 63845 | (573) 649-2193 |
| Free Will Baptist Church 208 Sycamore St, East Prairie 63845 | (573) 649-2622 |
| Full Gospel Church 514 N Garfield St, East Prairie 63845 | (573) 649-2167 |
| Jehovah's Witnesses Highway 80 W, East Prairie 63845 | (573) 649-5801 |
| Nelson Mem United Methodist 106 E Washington St, East Prairie 63845 | (573) 649-3969 |
| St James General Baptist 107 Truman St, East Prairie 63845 | (573) 649-2089 |
| Victory Baptist Church Highway 80 W, East Prairie 63845 | (573) 649-5689 |