| Business | Phone |
| Daeoc Community Action Agency 115 N Lincoln St, East Prairie 63845 | (573) 649-2441 |
| Delta Headstart 115 N Lincoln St, East Prairie 63845 | (573) 649-5005 |
| Mississippi County Family Svc 718 N Martin St, East Prairie 63845 | (573) 649-3091 |
| Susanna Wesley Learning Ctr 207 N Washington St, East Prairie 63845 | (573) 649-3731 |