| Business | Phone |
| Southeast Missouri Residential 112 Plaza Dr, Sikeston 63801 | (573) 472-5305 |
| Sikeston Regional Ctr-Disabled 112 Plaza Dr, Sikeston 63801 | (573) 472-5300 |
| Missouri Career Ctr 202 S Kingshighway St, Sikeston 63801 | (573) 472-5250 |
| Construction Project Office 2275 N Main St, Sikeston 63801 | (573) 472-5325 |
| Construction Project Office 2675 N Main St, Sikeston 63801 | (573) 472-5325 |