| Business | Phone |
| Cooperative Extension Cancer 110 North St, Wilkesboro 28697 | (336) 651-7595 |
| Cooperative Extension Svc 110 North St # 308, Wilkesboro 28697 | (336) 651-7331 |
| Finance Office 110 North St, Wilkesboro 28697 | (336) 651-7321 |
| Wilkes County Animal Shelter 408 Call St, Wilkesboro 28697 | (336) 903-7688 |
| Wilkes County Appraisal Dept 110 North St # 209, Wilkesboro 28697 | (336) 651-7301 |
| Wilkes County Board-Elections 110 North St, Wilkesboro 28697 | (336) 651-7339 |
| Wilkes County Building Inspctn 110 North St # 311, Wilkesboro 28697 | (336) 651-7303 |
| Wilkes County Cooperative Ext Wilkesboro 28697 | (336) 903-7600 |
| Wilkes County Elections Board 110 North St # 315, Wilkesboro 28697 | (336) 651-7338 |
| Wilkes County Extension Home 110 North St # 308, Wilkesboro 28697 | (336) 651-7330 |
| Wilkes County Finance Officer 110 North St # 115, Wilkesboro 28697 | (336) 651-7316 |
| Wilkes County Managers Office 110 North St # 101, Wilkesboro 28697 | (336) 651-7346 |
| Wilkes County Mapping Dept 110 North St # 212, Wilkesboro 28697 | (336) 651-7309 |
| Wilkes County Personnel Dept 110 North St # 103, Wilkesboro 28697 | (336) 651-7342 |
| Wilkes County Purchasing Dept 110 North St, Wilkesboro 28697 | (336) 651-7379 |
| Wilkes County Register Of Deed 500 Courthouse Dr # 1000, Wilkesboro 28697 | (336) 651-7351 |
| Wilkes County Road Names Addrs 110 North St, Wilkesboro 28697 | (336) 651-7388 |
| Wilkes County Superior Ct Clrk 500 Courthouse Dr # 1115, Wilkesboro 28697 | (336) 667-1201 |
| Veterans Service 110 North St, Wilkesboro 28697 | (336) 651-7327 |
| Schools Food Svc Warehouse Highway 268 E, Wilkesboro 28697 | (336) 667-2021 |
| Planning Dept 110 North St, Wilkesboro 28697 | (336) 651-7350 |