| Business | Phone |
| Cherokee Cnty Central Prchsng 210 N Limestone St, Gaffney 29340 | (864) 487-2777 |
| Cherokee Cnty Mntl Retardation 959 E Oneal St, Gaffney 29340 | (864) 489-1384 |
| Cherokee Cnty Veteran Affairs 1434 N Limestone St, Gaffney 29340 | (864) 487-2579 |
| Cherokee County Accntng Dept 210 N Limestone St, Gaffney 29340 | (864) 487-2592 |
| Cherokee County Addressing 122 Administrative Dr, Gaffney 29340 | (864) 487-2718 |
| Cherokee County Addressing 312 N Limestone St, Gaffney 29340 | (864) 487-2718 |
| Cherokee County Administration 210 N Limestone St, Gaffney 29340 | (864) 487-2560 |
| Cherokee County Animal Control 127 E Floyd Baker Blvd, Gaffney 29340 | (864) 487-8529 |
| Cherokee County Animal Control 300 Yale St, Gaffney 29341 | (864) 487-8529 |
| Cherokee County Animal Shelter 300 Yale St, Gaffney 29341 | (864) 487-2758 |
| Cherokee County Bldg Inspector 208 E Floyd Baker Blvd, Gaffney 29340 | (864) 487-2561 |
| Cherokee County Code Enforcemt 210 N Limestone St, Gaffney 29340 | (864) 487-8529 |
| Cherokee County Communications 122 Administrative Dr, Gaffney 29340 | (864) 487-2743 |
| Cherokee County Coroner 312 E Frederick St, Gaffney 29340 | (864) 487-6225 |
| Cherokee County Council 210 N Limestone St, Gaffney 29340 | (864) 487-2562 |
| Cherokee County Election Comm 1434 N Limestone St, Gaffney 29340 | (864) 487-2559 |
| Cherokee County Emergency 1434 N Limestone St, Gaffney 29340 | (864) 487-2542 |
| Cherokee County Extension Office 1100 W Floyd Baker Blvd, Gaffney 29341 | (864) 489-3141 |
| Cherokee County Juvenile Svc 312 E Frederick St, Gaffney 29340 | (864) 487-2564 |
| Cherokee County Landfill 192 Lemuels Rd, Gaffney 29341 | (864) 487-2537 |
| Cherokee County Personnel 210 N Limestone St, Gaffney 29340 | (864) 487-2795 |
| Cherokee County Recycling Center 1602 Overbrook Dr, Gaffney 29341 | (864) 487-2760 |
| Cherokee County Support Office 125 E Floyd Baker Blvd, Gaffney 29340 | (864) 487-2577 |
| Cherokee Emergency Operations 1434 N Limestone St, Gaffney 29340 | (864) 487-2590 |
| Cherokee Maintenance Dept 138 Public Works Dr, Gaffney 29341 | (864) 487-2535 |
| Cherokee Soil & Water Cnsrvtn 1252 Overbrook Dr # 5, Gaffney 29341 | (864) 489-7150 |
| Cherokee Solicitor's Office 125 E Floyd Baker Blvd, Gaffney 29340 | (864) 487-2576 |
| Cherokee Voter Registration 1434 N Limestone St, Gaffney 29340 | (864) 487-2563 |
| Cherokee Youth Sports Complex 230 Midway Rd, Gaffney 29341 | (864) 902-1113 |
| Public Defenders 310 N Limestone St # B1, Gaffney 29340 | (864) 487-6201 |