| Business | Phone |
| Adlerian Child Care Center 7817 Broad River Rd, Irmo 29063 | (803) 781-2111 |
| Children's House Of Irmo 5 Thames Valley Rd, Irmo 29063 | (803) 781-2056 |
| Children's World Learning Center 7624 Woodrow St, Irmo 29063 | (803) 781-4889 |
| Fantasy Island Day Care 7422 Childs St, Irmo 29063 | (803) 781-0061 |
| Farrow Hills Day Care 7422 Childs St, Irmo 29063 | (803) 691-1097 |
| Gap Center 105 Ministry Dr, Irmo 29063 | (803) 732-4287 |
| La Petite Academy 101 N Royal Tower Dr, Irmo 29063 | (803) 732-0159 |
| Picket Fences Christian Acad 138 Friarsgate Blvd, Irmo 29063 | (803) 732-0399 |
| Sunshine House 915 Kennerly Rd, Irmo 29063 | (803) 781-1734 |
| Wee Care Child Development Center 97 Riverwalk Way, Irmo 29063 | (803) 781-5439 |