| Business | Phone |
| Ambassador Christian Center 401 Western Ln, Irmo 29063 | (803) 749-0829 |
| Apostolic Temple Church 928 Kennerly Rd, Irmo 29063 | (803) 781-2110 |
| Ballentine Church Of Christ 1191 Dutch Fork Rd, Irmo 29063 | (803) 781-2022 |
| Bethlehem Lutheran Church 10000 Broad River Rd, Irmo 29063 | (803) 781-3900 |
| Cathedral Faith 1016 Rah Rah Way, Irmo 29063 | (803) 781-1344 |
| Christ Church Of Irmo 25 Blue Bird Trl, Irmo 29063 | (803) 749-9119 |
| Church Of A Second Chance 7971 Woodrow St, Irmo 29063 | (803) 732-1355 |
| Church Of Jesus Christ Of Lds 7449 Broad River Rd, Irmo 29063 | (803) 732-0259 |
| Dutch Fork Baptist Pre-School 3433 Dreher Shoals Rd, Irmo 29063 | (803) 781-2532 |
| Dutch Fork Christian Church 220 N World Tower Rd, Irmo 29063 | (803) 781-2211 |
| East Lake Community Church 10057 Broad River Rd, Irmo 29063 | (803) 749-9298 |
| Faith Presbyterian Church 1811 Dutch Fork Rd, Irmo 29063 | (803) 732-1234 |
| Family Worship Center 10501 Broad River Rd, Irmo 29063 | (803) 749-6800 |
| Gateway Baptist Church 7820 Broad River Rd, Irmo 29063 | (803) 732-6723 |
| Grace Covenant Church Po Box 329, Irmo 29063 | (803) 781-7115 |
| Hope Lutheran Church 1400 Kennerly Rd, Irmo 29063 | (803) 781-8673 |
| Hopewell Ame Church Hopewell Church Rd, Irmo 29063 | (803) 345-3706 |
| Inner Court Ministries 7701 Saint Andrews Rd, Irmo 29063 | (803) 781-8911 |
| Irmo Church Of God 10215 Broad River Rd, Irmo 29063 | (803) 732-4442 |
| Jehovah's Witnesses 7445 Broad River Rd, Irmo 29063 | (803) 781-6632 |
| Kennerly Road Baptist Church 1526 Kennerly Rd, Irmo 29063 | (803) 732-9797 |
| Lakewood Church 411b Western Ln, Irmo 29063 | (803) 732-4700 |
| Macedonia Baptist Church 1150 Lake Murray Blvd, Irmo 29063 | (803) 749-4480 |
| New Life Community Church 10809 Broad River Rd, Irmo 29063 | (803) 749-0220 |
| River Of Life Ministries 90 N Royal Tower Dr, Irmo 29063 | (803) 407-4774 |
| River Springs Church 1007 W Shady Grove Rd, Irmo 29063 | (803) 407-6310 |
| Saint Paul Ame Church 835 Kennerly Rd, Irmo 29063 | (803) 781-7805 |
| Salem United Methodist Church 1321 Salem Church Rd, Irmo 29063 | (803) 781-1626 |
| Salvation Army 7532 Irmo Dr, Irmo 29063 | (803) 781-1511 |
| Shady Grove United Methodist 1918 Shady Grove Rd, Irmo 29063 | (803) 781-4832 |
| St James Fire Baptized 1016 Kinley Rd, Irmo 29063 | (803) 781-7344 |
| St John's Lutheran Church 1028 Saint Johns Rd, Irmo 29063 | (803) 781-3311 |
| St Paul Ame Church 835 Kennerly Rd, Irmo 29063 | (803) 781-0906 |
| St Peter Baptist Church 7910 Broad River Rd, Irmo 29063 | (803) 781-1067 |
| St Simon & St Jude Episcopal 1110 Kinley Rd, Irmo 29063 | (803) 732-0153 |
| Standing Stones Christian Chr 208 Saint Stephens E, Irmo 29063 | (803) 749-1991 |
| Three Rivers Baptist Church 7452 Broad River Rd, Irmo 29063 | (803) 781-2293 |
| Young's Chapel Ame Church 7336 Carlisle St, Irmo 29063 | (803) 732-5858 |
| Young's Chapel Ame Church Kinley Rd, Irmo 29063 | (803) 732-5858 |
| Union United Methodist Church 7582 Woodrow St, Irmo 29063 | (803) 781-3013 |
| Universal Outreach Church 7232 Broad River Rd, Irmo 29063 | (803) 749-0213 |
| Victory Bible Church 10245 Broad River Rd, Irmo 29063 | (803) 781-6970 |