| Business | Phone |
| Caring & Sharing Daycare 111 Rural Ave, Manning 29102 | (803) 435-2760 |
| Free Spirits Child Day Care 715 N Brooks St, Manning 29102 | (803) 435-0008 |
| Kids Fantasy Land Daycare 2197 N Brooks St, Manning 29102 | (803) 433-5424 |
| Kids' World Day Care 1947 Ellis Hwy, Manning 29102 | (803) 473-4775 |
| Kids' World Day Care 4072 Alex Harvin Hwy, Manning 29102 | (803) 473-4775 |
| Precious Angels Daycare 1079 Capital Way, Manning 29102 | (803) 435-6799 |
| Wee Academy Learning Center 566 Sunset Dr, Manning 29102 | (803) 435-8340 |
| Wee Academy Learning Center 625 W Huggins St, Manning 29102 | (803) 435-2071 |