| Business | Phone |
| After School Kid Center 210 Balcome Blvd, Simpsonville 29681 | (864) 967-2891 |
| Classy Kids Child Dev Center 678 Fairview Rd, Simpsonville 29680 | (864) 967-2888 |
| Classy Kids Child Dev Center 911 W Georgia Rd, Simpsonville 29680 | (864) 228-3663 |
| First Baptist Church Day Care 106 Church St, Simpsonville 29681 | (864) 228-0972 |
| Golden Rule Child Development 504 Boyd Ave, Simpsonville 29681 | (864) 967-4043 |
| Heavens Child Learning Center 3421 N Industrial Dr, Simpsonville 29681 | (864) 962-1111 |
| Holy Cross Academy 203 E College St, Simpsonville 29681 | (864) 963-5986 |
| Jesus Precious Little Angels 232 Moore St, Simpsonville 29681 | (864) 963-0171 |
| Kids Place 304 Balcome Blvd, Simpsonville 29681 | (864) 967-7537 |
| Nannys Plus Domestic Agency 511 W Yellow Wood Dr, Simpsonville 29680 | (864) 242-1943 |
| Small Wonders Family Daycare 207 Kincade Dr, Simpsonville 29681 | (864) 329-1808 |