| Business | Phone |
| Hampton County Animal Shelter 460 Cemetery Rd, Varnville 29944 | (803) 943-7567 |
| Hampton County Victim Advocate 411 Cemetery Rd, Varnville 29944 | (803) 943-3094 |
| Hampton Disabilties & Special 210 Hampton Rd, Varnville 29944 | (803) 943-5711 |
| Palmetto Development Center 210 Hampton Rd, Varnville 29944 | (803) 943-4818 |
| Varnville Community Residence 266 Hampton Rd, Varnville 29944 | (803) 943-3504 |