| Business | Phone |
| Best Western Inn Rr 1 Box 52b, Yemassee 29945 | (843) 726-8101 |
| Days Inn 3196 Point South Dr, Yemassee 29945 | (843) 726-8156 |
| Group South Hotels Inc 139 Frampton Dr, Yemassee 29945 | (843) 726-9222 |
| Holiday Inn Express Pt South 138 Frampton Dr, Yemassee 29945 | (843) 726-9400 |
| Knights Inn Us Highway 17, Yemassee 29945 | (843) 726-8488 |
| Palmetto Lodge 12 Lane St, Yemassee 29945 | (843) 589-2361 |
| Simmons Truck Stop & Motel 112 Jackson St, Yemassee 29945 | (843) 589-3400 |
| Super 8 Motels 409 Yemassee Hwy, Yemassee 29945 | (843) 589-2177 |