| Business | Phone |
| Community Medical Clinic 1000 S Texas St, De Leon 76444 | (254) 893-3509 |
| Crosstimbers Health Clinic 1100 W Reynosa, De Leon 76444 | (254) 893-5895 |
| De Leon Clinic 425 S Texas St, De Leon 76444 | (254) 893-2051 |
| Wic-Crosstimbers Clinic 1100 E Reynosa Ave, De Leon 76444 | (254) 893-5926 |
| A E Pino Clinic 224 N Texas St, De Leon 76444 | (254) 893-2097 |