| Business | Phone |
| Emergency Medical Svc Office 500 E San Antonio St # 5, Pearsall 78061 | (830) 334-3201 |
| Frio County 911 Addressing Office 2207 Business Interstate 35 E, Pearsall 78061 | (830) 334-0088 |
| Frio County Alcohol Prevention Frio County Courthouse, Pearsall 78061 | (830) 334-0010 |
| Frio County Appraisal Dist Office 815 S Oak St, Pearsall 78061 | (830) 334-4163 |
| Frio County Detention Facility 410 S Cedar St, Pearsall 78061 | (830) 334-3320 |
| Frio County Extension Agent 400 S Pecan St, Pearsall 78061 | (830) 334-0099 |
| Frio County Justice Of Peace 2207 Interstate 35 E, Pearsall 78061 | (830) 334-8292 |
| Frio County Justice Of Peace 411 N Willow St # 10, Pearsall 78061 | (830) 334-2911 |
| Frio County Justice Of Peace 500 E San Antonio St # 9, Pearsall 78061 | (830) 334-3668 |
| Frio County Road & Bridge 2207 Business Interstate 35 E, Pearsall 78061 | (830) 334-0085 |
| Frio Extension Pest Management 406 S Pecan St, Pearsall 78061 | (830) 334-3290 |
| Frio Housing Rehab Program Frio County Courthouse, Pearsall 78061 | (830) 334-0098 |