| Business | Phone |
| First National Bank 123 Queen Isabella Blvd, Port Isabel 78578 | (956) 389-7330 |
| First National Bank-Md 218 E Queen Isabella Blvd, Port Isabel 78578 | (956) 943-1190 |
| First National Bank-Edinburg 123 W Queen Isabella Blvd, Port Isabel 78578 | (956) 943-1227 |
| Ibc Bank 1401 State Highway 100, Port Isabel 78578 | (956) 943-2108 |
| International Bank Of Commerce 302 E Queen Isabella Blvd, Port Isabel 78578 | (956) 943-3000 |
| Wells Fargo Bank 800 Highway 100, Port Isabel 78578 | (956) 943-0250 |
| Wells Fargo Bank 800 State Highway 100, Port Isabel 78578 | (956) 943-0252 |