| Business | Phone |
| Big Stone Gap Pharmacy 1980 Holton Ave E, Big Stone Gap 24219 | (276) 523-8702 |
| Valley Discount Pharmacy Inc 526 Wood Ave, Big Stone Gap 24219 | (276) 523-4795 |
| Family Drug Inc 3169 2nd Ave E, Big Stone Gap 24219 | (276) 523-1713 |
| Food City 891 Pharmacy 603 Wood Ave, Big Stone Gap 24219 | (276) 523-6052 |
| Mutual Drug 314 Wood Ave E, Big Stone Gap 24219 | (276) 523-1123 |