| Business | Phone |
| B B & T 1055 E Main St, Wytheville 24382 | (276) 223-7204 |
| B B & T 1105 N 4th St, Wytheville 24382 | (276) 228-6021 |
| B B & T 170 E Main St, Wytheville 24382 | (276) 228-5464 |
| Bank Of America 210 E Main St, Wytheville 24382 | (276) 223-6150 |
| National Bank 185 E Main St, Wytheville 24382 | (276) 228-5451 |
| Blue Ridge Bank Na 325 E Spring St, Wytheville 24382 | (276) 223-1900 |
| First Trust Bank 150 W Main St, Wytheville 24382 | (276) 228-1125 |
| First Century Bank 200 Peppers Ferry Rd, Wytheville 24382 | (276) 223-1115 |
| First Community Bank 910 E Main St, Wytheville 24382 | (276) 228-1900 |
| First National Bank-Md 320 W Main St, Wytheville 24382 | (276) 228-5433 |
| First National Bank-Md 900 N 4th St, Wytheville 24382 | (276) 625-0838 |