| Business | Phone |
| Ona's Country Kitchen 261 Farm Fields Ln, Wytheville 24382 | (276) 579-4440 |
| Brick 330 Valley St, Wytheville 24382 | (434) 286-9500 |
| Clinic Pub & Eatery 195 W Main St, Wytheville 24382 | (276) 228-9111 |
| E N Umberger Store-Skeeter's 165 E Main St, Wytheville 24382 | (276) 228-2611 |
| Family Restaurant Office 270 Echo Valley Rd, Wytheville 24382 | (276) 228-8303 |
| El Puerto 715 Chapman Rd, Wytheville 24382 | (276) 228-3159 |
| Log House 1776 Restaurant 520 E Main St, Wytheville 24382 | (276) 228-4139 |
| Mario's Pizza 100 W Main St, Wytheville 24382 | (276) 228-1212 |
| Old Stage Restaurant 155 W Marshall St, Wytheville 24382 | (276) 228-8990 |
| Paisano's 1380 E Main St, Wytheville 24382 | (276) 228-5555 |
| Wohlfahrt Haus Dinner Theater 170 Malin Dr, Wytheville 24382 | (276) 223-0891 |
| Virginia Heights Restaurant 790 W Spiller St, Wytheville 24382 | (276) 228-6133 |
| Tj Cinnamons 1318 E Lee Hwy, Wytheville 24382 | (276) 228-2518 |
| Travel Centers Of America 1025 Peppers Ferry Rd, Wytheville 24382 | (276) 228-9437 |
| Turn One Restaurant 1155 N 4th St, Wytheville 24382 | (276) 228-8876 |
| Squire's Tavern 155 E Main St, Wytheville 24382 | (276) 228-9700 |
| Subway Sandwich Shop 345 Commonwealth Dr, Wytheville 24382 | (276) 228-7117 |
| Sonic Drive In Restaurant 790 E Main St, Wytheville 24382 | (276) 228-2581 |
| Spiller Primary Sch Cafeteria 330 Tazewell St, Wytheville 24382 | (276) 228-4791 |
| Applebee's Neighborhood Grill 1440 E Main St, Wytheville 24382 | (276) 223-4404 |
| Arby's Roast Beef 1040 N 4th St, Wytheville 24382 | (276) 228-2951 |
| Arby's 1290 E Lee Hwy, Wytheville 24382 | (276) 228-2518 |
| Bob Evans Restaurant 190 Lithia Rd, Wytheville 24382 | (276) 228-6999 |
| Burger King 3223 Chapman Rd, Wytheville 24382 | (276) 228-6898 |
| C J's Pizza 1025 W Lee Hwy, Wytheville 24382 | (276) 228-8448 |
| China Wok Restaurant 330 Commonwealth Dr, Wytheville 24382 | (276) 228-8886 |
| Country Kitchen Restaurant 955 Peppers Ferry Rd, Wytheville 24382 | (540) 228-0884 |
| Cracker Barrel Old Country Str 160 Lithia Rd, Wytheville 24382 | (276) 228-1046 |
| Dairy Queen 1190 E Main St, Wytheville 24382 | (276) 228-6020 |
| Dairy Queen 1290 E Lee Hwy, Wytheville 24382 | (276) 228-2522 |
| Fran's Dutch Foods 545 E Main St, Wytheville 24382 | (276) 228-6105 |
| Glisan's Restaurant & Bbq 100 Grayson Rd, Wytheville 24382 | (276) 228-5308 |
| Hardee's 1015 E Main St, Wytheville 24382 | (276) 228-7292 |
| Interstate Brands Corp 860 Stafford Umberger Rd, Wytheville 24382 | (276) 228-7555 |
| Kfc 1910 E Main St, Wytheville 24382 | (276) 228-7321 |
| Little Caesar's Pizza 215 Commonwealth Dr, Wytheville 24382 | (276) 228-8899 |
| Long John Silver's Seafood 880 E Main St, Wytheville 24382 | (276) 228-8481 |
| Mc Donald's Hamburgers 1195 N 4th St, Wytheville 24382 | (276) 228-5714 |
| Ocean Bay Seafood 1505 E Main St, Wytheville 24382 | (276) 228-5300 |
| Papa John's Pizza 130 Cassell Rd, Wytheville 24382 | (276) 625-7272 |
| Peking Chinese Restaurant 105 Malin Dr, Wytheville 24382 | (276) 228-5515 |
| Wendys Old Fashion Hamburgers 955 E Main St, Wytheville 24382 | (276) 228-7877 |
| Waffle House Restaurant 1975 E Main St, Wytheville 24382 | (276) 228-7767 |
| Pizza Hut 225 W Lee Hwy, Wytheville 24382 | (276) 228-7127 |
| Quiznos Sub 1455 E Main St, Wytheville 24382 | (276) 228-7849 |
| Taco Bell 1025 Peppers Ferry Rd, Wytheville 24382 | (276) 228-0070 |
| Ruby Tuesday Restaurant 145 Commonwealth Dr, Wytheville 24382 | (276) 223-4380 |
| Sagebrush Steakhouse & Saloon 170 Nye Cir, Wytheville 24382 | (276) 228-7103 |
| Subway Sandwich Shop 215 Commonwealth Dr, Wytheville 24382 | (276) 228-4848 |
| Shoney's Restaurant 120 Malin Dr, Wytheville 24382 | (276) 228-5667 |
| Smokey's Bar-B-Q 255 Holston Rd, Wytheville 24382 | (276) 228-9014 |
| Smokeys Bbq 205 Fairground Rd, Wytheville 24382 | (276) 228-9014 |